Semax

Research Peptide

Also known as: MEHFPGP

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What is Semax?

Semax is a synthetic peptide derived from ACTH with nootropic and neuroprotective properties. It is approved in Russia for stroke and cognitive disorders.

How It Works

Semax increases BDNF levels, modulates serotonin and dopamine, and has neuroprotective effects by reducing oxidative stress.

What Research Shows

40
Animal Studies
20
Human Studies

Key Findings:

  • Approved for cognitive disorders in Russia
  • Increases BDNF expression
  • May improve attention and memory

Limited Human Research

Most research on Semax has been conducted in animal models. Human clinical trials are limited or absent. Results may not translate directly to humans.

Dosing Protocol

Typical Dose
200-600 mcg
Frequency
2-3 times daily
Route
Intranasal
Duration
2-4 weeks

These are general guidelines based on research literature and community protocols. Individual dosing should be determined by a qualified healthcare provider.

Safety & Risks

Reported Side Effects:

Nasal irritationHeadacheDizziness

Contraindications:

  • Pregnancy
  • Acute psychosis
  • Severe hypertension

Important: This information is for research purposes only. Always consult with a qualified healthcare provider before using any peptide. Never use peptides without proper medical supervision.

Sourcing & Quality

Quality varies significantly between peptide sources. When sourcing Semax, consider:

  • Third-party testing (HPLC, Mass Spectrometry)
  • Certificate of Analysis (CoA) availability
  • Purity levels (>98% recommended)
  • Beware of LPS (endotoxin) contamination

CalcPep does not sell peptides or recommend specific vendors. Always verify product quality through independent testing.

Quick Facts
Category
Cognitive
Status
Research Only
Typical Dose
200-600 mcg
Route
Intranasal
Duration
2-4 weeks
Real-World Data
1,023
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