CalcPep Research

PT-141

FDA Approved

Also known as: Bremelanotide, Vyleesi

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What is PT-141?

PT-141 (Bremelanotide) is an FDA-approved peptide for treating hypoactive sexual desire disorder (HSDD) in premenopausal women.

How It Works

PT-141 activates melanocortin receptors in the central nervous system, affecting sexual arousal pathways.

What Research Shows

30
Animal Studies
15
Human Studies

Key Findings:

  • FDA-approved for HSDD in women
  • Increases sexual desire in clinical trials
  • Works through CNS mechanisms

Dosing Protocol

Typical Dose
1-2 mg
Frequency
As needed (at least 45 min before activity)
Route
Subcutaneous injection
Duration
As needed

These are general guidelines based on research literature and community protocols. Individual dosing should be determined by a qualified healthcare provider.

Safety & Risks

Reported Side Effects:

NauseaFlushingHeadacheInjection site reactions

Contraindications:

  • Uncontrolled hypertension
  • Cardiovascular disease

Important: This information is for research purposes only. Always consult with a qualified healthcare provider before using any peptide. Never use peptides without proper medical supervision.

Sourcing & Quality

Quality varies significantly between peptide sources. When sourcing PT-141, consider:

  • Third-party testing (HPLC, Mass Spectrometry)
  • Certificate of Analysis (CoA) availability
  • Purity levels (>98% recommended)
  • Beware of LPS (endotoxin) contamination

CalcPep does not sell peptides or recommend specific vendors. Always verify product quality through independent testing.

Quick Facts
Category
Sexual Health
Status
FDA Approved
Typical Dose
1-2 mg
Route
Subcutaneous injection
Duration
As needed
Real-World Data
987
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