MOTS-c

Research Peptide

Also known as: Mitochondrial ORF of the 12S rRNA type-c

What is MOTS-c?

MOTS-c is a mitochondrial-derived peptide that plays a role in metabolic regulation, exercise mimetic effects, and potentially longevity.

How It Works

MOTS-c activates AMPK pathways, enhances glucose metabolism, and improves insulin sensitivity. It may also promote mitochondrial biogenesis.

What Research Shows

Animal Studies

Human Studies

Key Findings:

Improves glucose metabolism in mice
May enhance exercise capacity
Shows potential anti-aging effects in animal models

Limited Human Research

Most research on MOTS-c has been conducted in animal models. Human clinical trials are limited or absent. Results may not translate directly to humans.

Dosing Protocol

Typical Dose

5-10 mg

Frequency

2-3 times weekly

Route

Subcutaneous injection

Duration

8-12 weeks

These are general guidelines based on research literature and community protocols. Individual dosing should be determined by a qualified healthcare provider.

Safety & Risks

Reported Side Effects:

Injection site reactionMild fatigue

Contraindications:

Pregnancy
Active cancer

Important: This information is for research purposes only. Always consult with a qualified healthcare provider before using any peptide. Never use peptides without proper medical supervision.

Sourcing & Quality

Quality varies significantly between peptide sources. When sourcing MOTS-c, consider:

Third-party testing (HPLC, Mass Spectrometry)
Certificate of Analysis (CoA) availability
Purity levels (>98% recommended)
Beware of LPS (endotoxin) contamination

CalcPep does not sell peptides or recommend specific vendors. Always verify product quality through independent testing.

Quick Facts

Track Your Protocol

Use CalcPep to calculate doses, log injections, and track your progress.

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