Argireline

Research Peptide

Also known as: Acetyl Hexapeptide-3, Acetyl Hexapeptide-8

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What is Argireline?

Argireline is a popular cosmetic peptide that reduces expression wrinkles by inhibiting neuromuscular junction activity.

How It Works

Argireline inhibits SNARE complex formation, reducing acetylcholine release and muscle contraction for a mild botox-like effect.

What Research Shows

8
Animal Studies
12
Human Studies

Key Findings:

  • 30% wrinkle reduction in some studies
  • Well-established safety profile
  • Popular in anti-aging cosmetics

Limited Human Research

Most research on Argireline has been conducted in animal models. Human clinical trials are limited or absent. Results may not translate directly to humans.

Dosing Protocol

Typical Dose
5-10 % solution
Frequency
Twice daily
Route
Topical
Duration
Ongoing

These are general guidelines based on research literature and community protocols. Individual dosing should be determined by a qualified healthcare provider.

Safety & Risks

Reported Side Effects:

Mild skin irritation (rare)

Contraindications:

  • Peptide allergies

Important: This information is for research purposes only. Always consult with a qualified healthcare provider before using any peptide. Never use peptides without proper medical supervision.

Sourcing & Quality

Quality varies significantly between peptide sources. When sourcing Argireline, consider:

  • Third-party testing (HPLC, Mass Spectrometry)
  • Certificate of Analysis (CoA) availability
  • Purity levels (>98% recommended)
  • Beware of LPS (endotoxin) contamination

CalcPep does not sell peptides or recommend specific vendors. Always verify product quality through independent testing.

Quick Facts
Category
Cosmetic
Status
Research Only
Typical Dose
5-10 % solution
Route
Topical
Duration
Ongoing
Real-World Data
567
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