CalcPep Research
Comparison

BPC-157 vs TB-500: Which Healing Peptide is Right for You?

BPC-157 and TB-500 are the two most popular healing peptides, often used together. BPC-157 excels at localized tissue repair and gut healing, while TB-500 provides more systemic healing effects and flexibility improvements.

BPC-157
Typical Dose: 250-500 mcg
Frequency: Once or twice daily
Route: Subcutaneous injection
FDA Approved: No
View BPC-157 Details
TB-500
Typical Dose: 2-5 mg
Frequency: Twice weekly
Route: Subcutaneous injection
FDA Approved: No
View TB-500 Details
Key Differences
AspectBPC-157TB-500
MechanismPromotes angiogenesis, modulates nitric oxideUpregulates actin, promotes cell migration
Dosing250-500 mcg daily2-5 mg twice weekly
Best ForLocalized injuries, gut healingSystemic healing, flexibility
Research Base47 animal studies, 0 human32 animal studies, 0 human
CostLower (smaller doses needed)Higher (larger doses needed)
When to Use Each

BPC-157 May Be Better For:

  • Localized tendon/ligament injuries
  • Gut healing and gastroprotection
  • Joint-specific injuries
  • Post-surgical recovery (localized)

TB-500 May Be Better For:

  • Systemic healing needs
  • Flexibility and mobility issues
  • Cardiac tissue support
  • Widespread inflammation

Both Are Good For:

General injury recoveryMuscle tearsChronic pain conditionsAthletic recovery protocols
Side Effects Comparison

BPC-157

  • Injection site reaction
  • Mild fatigue
  • Headache

TB-500

  • Injection site irritation
  • Temporary lethargy
  • Head rush
The Verdict

For localized injuries (specific tendon, joint, or gut issues), BPC-157 is typically preferred. For systemic healing or when flexibility is a concern, TB-500 may be better. Many users combine both for synergistic effects.

Research Data

BPC-157

47
Animal Studies
0
Human Studies

TB-500

32
Animal Studies
0
Human Studies
Dosing Tools
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Research Purposes Only

This comparison is for educational purposes. Consult a healthcare provider before using any peptides.